ABSTRACT
On 19 September 2020, the Centers for Disease Control and Prevention (CDC) recommended that asymptomatic individuals, those who have close contact with infected person, be tested. Also, American society for biological clinical comments on testing of asymptomatic individuals. So, we proposed a new mathematical model for evaluating the population-level impact of contact rates (social-distancing) and the rate at which asymptomatic people are hospitalized (isolated) following testing due to close contact with documented infected people. The model is a deterministic system of nonlinear differential equations that is fitted and parameterized by least square curve fitting using COVID-19 pandemic data of Pakistan from 1 October 2020 to 30 April 2021. The fractional derivative is used to understand the biological process with crossover behavior and memory effect. The reproduction number and conditions for asymptotic stability are derived diligently. The most common non-integer Caputo derivative is used for deeper analysis and transmission dynamics of COVID-19 infection. The fractional-order Adams-Bashforth method is used for the solution of the model. In light of the dynamics of the COVID-19 outbreak in Pakistan, non-pharmaceutical interventions (NPIs) in terms of social distancing and isolation are being investigated. The reduction in the baseline value of contact rates and enhancement in hospitalization rate of symptomatic can lead the elimination of the pandemic.
ABSTRACT
In December 2019, in Wuhan, China, a new disease was detected, and the virus easily spread throughout other nations. March 2, 2020, Morocco announced 1st infection of coronavirus. Morocco verified a total of 653,286 cases, 582,692 recovered, 60,579 active case, and 10,015 as confirmatory fatalities, as of 4 August 2021. The objective of this article is to study the mathematical modeling of undetected cases of the novel coronavirus in Morocco. The model is shown to have disease-free and an endemic equilibrium point. We have discussed the local and global stability of these equilibria. The parameters of the model and undiscovered instances of COVID-19 were assessed by the least squares approach in Morocco and have been eliminated. We utilized a Matlab tool to show developments in undiscovered instances in Morocco and to validate predicted outcomes. Like results, until August 4, 2021, the total number of infected cases of COVID-19 in Morocco is 24,663,240, including 653,286 confirmed cases, against 24,009,954 undetected. Further, our approach gives a good approximation of the actual COVID-19 data from Morocco and will be used to estimate the undetected cases of COVID-19 in other countries of the world and to study other pandemics that have the same nature of spread as COVID-19.